Now revised and expanded with over 50% new material, this definitive clinical reference is the text of choice for graduate-level courses in evidence-based psychotherapy. Foremost authorities describe the conceptual and scientific foundations of cognitive-behavioral therapy (CBT) and provide a framework for assessment and case formulation. Major approaches are reviewed in detail, including emotion centered problem-solving therapy, rational emotive behavior therapy, cognitive therapy, schema therapy, mindfulness- and acceptance-based interventions, and dialectical behavior therapy (DBT). Applications to specific populations are discussed, including children and adolescents, couples, culturally diverse clients, and more.