Click Chemistry has rapidly established a prominent role in materials science, medicinal, and bio conjugation chemistry. It is important to recognize that click reactions achieve their required characteristics by having a high thermodynamic driving force, usually greater than 20 kcal/mol. This book discusses click chemistry reactions that proceed rapidly with high selectivity, specificity, and yield. In this book, important aspects of click chemistry will be discussed, along with its emerging applications in drug delivery and nanomedicine.