The importance of computer simulations in understanding cellular processes is now widely accepted; a variety of algorithms have been developed to study these biological networks. This progressive book presents the basic principles of proper statistical analyses. It progresses to more advanced statistical methods in response to rapidly developing technologies and methodologies in the field of molecular biology. This book will serve for students and practitioners in the areas of statistics, biostatistics, computer science, and related fields in applied mathematics; this book presents various approaches to help students solve problems at the interface of these areas.